번호 |
물질 |
독성자료가 있는 동물종 |
1 |
Acacia |
Nonhuman primate, rat |
2 |
Acetate buffer |
Nonhuman primate, minipig, mouse, rat |
3 |
Acetic acid |
Dog, mouse, rat |
4 |
Acetone |
Guinea pig, mouse, rabbit, rat |
5 |
Acetonitrile |
Dog |
6 |
Acetylated lanolin alcochol |
Minipig |
7 |
Acetylmethylamide |
Nonhuman primate |
8 |
Alcohol denatured SDA |
Minipig |
9 |
Alginic acid |
Rat |
10 |
Anecortave acetate |
Rat |
11 |
Antifoam 1510-USTM |
Rat |
12 |
Avicel CL-611TM |
Dog |
13 |
Balanced salt saline |
Rabbit |
14 |
Basal salt solution |
Mouse |
15 |
Benzonic acid |
Rat |
16 |
Benzyl alcohol |
Cat, Dog, nonhuman primate, rat |
17 |
β-Cyclodextrin |
Dog, mouse, nonhuman primate, rat |
18 |
BHA |
Minipig |
19 |
BHT |
Cat, Dog, nonhuman primate, rat |
20 |
Bicarbonate buffer |
Mouse |
21 |
Calcium chloride |
Mouse |
22 |
Canola oil |
Dog |
23 |
Capmul MCMTM |
Nonhuman primate |
24 |
Capmul MCM NFTM |
Dog, rat |
25 |
Capmul PG 8TM |
Dog, rat |
26 |
Capryol 90TM |
Dog, rabbit, rat |
27 |
CaptisolTM |
Dog, mouse, nonhuman primate, rat |
28 |
Carbomer 974PTM |
Minipig, mouse |
29 |
Carbopol Ultrez 10TM |
Minipig |
30 |
Carboxymethylcellulose |
Dog, minipig, mouse, nonhuman primate, rabbit, rat |
31 |
Carboxymethylcellulose calcium |
Dog |
32 |
Carboxymethylcellulose sodium |
Mouse, rabbit, rat |
33 |
CavisolTM |
Dog, rat |
34 |
Cetostearyl alcohol |
Minipig |
35 |
Cetyl acetate |
Minipig |
36 |
Cetyl alcohol |
Minipig, mouse |
37 |
Citrate buffer |
Dog, nonhuman primate, rat |
38 |
Citric acid buffer |
Cat, dog, nonhuman primate, rat |
39 |
Coconut oil |
Minipig |
40 |
Collagen matrix |
Nonhuman primate, rabbit |
41 |
Corn oil |
Chicken embryo, dog, mouse, nonhuman primate, rabbit rat |
42 |
Cottonseed oil |
Dog |
43 |
Cyclodextrin |
Rat |
44 |
Cyclohexane |
Rabbit, rat |
45 |
Cyclomethicone NF |
Minipig |
46 |
DAM |
Dog, rat |
47 |
Dextrose |
Cat, dog, minipig, nonhuman primate, rabbit, rat |
48 |
Dichlorvos |
Nonhuman primate |
49 |
Diethylacetamide |
Cat, chicken, dog, mouse, rabbit, rat |
50 |
Diethylene glycolmonoethyl ether |
Nonhuman primate |
51 |
Dimethicone |
Rabbit |
52 |
Dimethiconol blend 20 |
Minipig |
53 |
Dimethylacetamide |
Chicken, dog, mouse, rabbit, rat |
54 |
Dimethyl sulfoxide |
Dog, guinea pig, minipig, mouse, nonhuman primate, rabbit, rat |
55 |
Disodium hydrogen phosphate dihydrate |
Nonhuman primate |
56 |
Docosanol |
Minipig |
57 |
Dulbecco's modified PBS |
Rat |
58 |
Dulbecco's PBS |
Rat |
59 |
EDTA |
Minipig, nonhuman primate, rat |
60 |
Ethanol |
Dog, guinea pig, minipig, mouse, nonhuman primate, rat |
61 |
Fumaric acid |
Dog |
62 |
Gelatin |
Dog, nonhuman primate, |
63 |
Gelatin phosphate buffer |
Minipig |
64 |
GelucireTM |
Minipig |
65 |
Gelucire 44/14TM |
Dog, minipig, mouse, rabbit, rat |
66 |
Gelucire 50/13TM |
Rat |
67 |
Gluconic acid |
Dog, rat |
68 |
Glycerol |
Dog, guinea pig, minipig, mouse, nonhuman primate, rabbit, rat |
69 |
Glyceryl stearate SE |
Minipig |
70 |
Glycofurol |
Dog |
71 |
Glycol dimethacrylate crosspolymer |
Rat |
72 |
Gum tragacanth |
Mouse |
73 |
Gum xanthan |
Minipig, rabbit, rat |
74 |
Hexylene glycol |
Minipig |
75 |
Histidine |
Dog, rat |
76 |
Hydrochloric acid |
Dog, rat |
77 |
Hydrogenated castor oil |
Minipig |
78 |
Hydroxyethylcellulose |
Rat |
79 |
Hydroxypropyl β-cyclodextrin |
Dog, mouse, nonhuman primate, rat |
80 |
Hydroxypropyl cellulouse |
Minipig, rat |
81 |
Hydroxypropyl methylcellulose |
Dog, minipig, mouse, nonhuman primate, rat |
82 |
Hydroxypropyl methylcellulose acetate succinate |
Dog, minipig, mouse, rabbit, rat |
83 |
Hymetellose |
Rabbit |
84 |
Hypotonic PBS |
Dog, rat |
85 |
Imwitor 742TM |
Hamster, nonhuman primate, rat |
86 |
Isopropyl alcohol |
Dog, rabbit |
87 |
Isopropyl myristate |
Minipig, mouse, rabbit |
88 |
Isotonic saline |
Rat |
89 |
KolliphorTM |
Nonhuman primate |
90 |
Kolliphor ELTM |
Dog, mouse, nonhuman primate, rat |
91 |
Kolliphor ELPTM |
Dog |
92 |
Kolliphor HS15TM (see also Solutol HS15) |
Minipig |
93 |
Kolliphor RH40TM |
Dog, rat |
94 |
Labrafil M1944TM |
Dog, rabbit, rat |
95 |
LabrasolTM |
Dog, minipig, rabbit, rat |
96 |
Lactated Ringer's |
Nonhuman primate |
97 |
Lactic acid |
Dog, rat |
98 |
Lactose |
Dog, nonhuman primate, rat |
99 |
Lanolin |
Minipig, rabbit |
100 |
Lanolin alcohol NF |
Minipig |
101 |
L-Arginine HCl USP |
Minipig, nonhuman primate |
102 |
L-Ascorbic acid |
Rat |
103 |
Lauroglycol 90TM |
Rabbit, rat |
104 |
Maltitol solution |
Rat |
105 |
Maltol |
Guinea pig, rabbit |
106 |
Mannitol |
Dog, minipig, mouse, nonhuman primate, rabbit, rat |
107 |
Methanesulfonic acid |
Rat |
108 |
MethocelTM |
Nonhuman primat, rat |
109 |
Methyl methacrylate |
Rat |
110 |
Methylcellulose |
Dog, guinea pig, mouse, nonhuman primate, rabbit, rat |
111 |
Methylparaben |
Minipig |
112 |
Methylpyrrolidone |
Dog, minipig, mouse |
113 |
Mineral oil |
Cat, dog, guinea pig, minipig, mouse, rat |
114 |
Myristyl alcohol |
Minipig |
115 |
Neobell 1053 OilTM |
Mouse, rat |
116 |
Octoxynol-40 |
Dog, rabbit |
117 |
Oleic acid NF |
Minipig |
118 |
Oleyl alcohol NF |
Minipig |
119 |
Olive oil |
Minipig, rat |
120 |
Ora-PluseTM suspension |
Rat |
121 |
Panthenol |
Minipig |
122 |
Peanut oil |
Dog, rat |
123 |
Peceol |
Dog, rat |
124 |
PEG 200 |
Minipig, nonhumand primate, rabbit, rat |
125 |
PEG 300 |
Cat, dog, guinea pig, mouse, rabbit, rat |
126 |
PEG 400 |
Dog, guinea pig, minipig, mouse, nonhuman primate, minipig, rabbit, rat |
127 |
PEG 600 |
Rat |
128 |
PEG 810 |
Rat |
129 |
PEG 1000 |
Mouse, rabbit, rat |
130 |
PEG 1500 |
Rat |
131 |
PEG 1540 |
Dog, rabbit, rat |
132 |
PEG 4000 |
Dog, mouse, rabbit, rat |
133 |
PEG 6000 |
Rabbit, rat |
134 |
PEG 10000 |
Rat |
135 |
PEG 400000 |
Rat |
136 |
Petrolatum |
Rabbit |
137 |
Phenoxyethanol |
Minipig, mouse |
138 |
Phosal 53 MCTTM |
Rat |
139 |
Phosphate |
Nonhuman primate |
140 |
Phosphate buffer |
Rat |
141 |
Phosphate-buffered saline |
Dog, minipig, mouse, nonhuman primate, rabbit, rat |
142 |
Polawax |
Minipig, mouse |
143 |
Poloxamer 124TM |
Dog, mouse, rat |
144 |
Poloxamer 188TM |
Dog, minipig, mouse, nonhuman primate, rabbit, rat |
145 |
Polyethylene terephthalate |
Rat |
146 |
Poly(glycolide-co-DL-lactide) microspheres |
Dog |
147 |
Polyglyceyl oleate |
Rabbit, rat |
148 |
Polyvinylpyrrlidone |
Dog, nonhuman primate, rabbit, rat |
149 |
Potassium chloride |
Minipig |
150 |
Propylene glycol |
Dog, minipig, puinea pig, nonhuman primate, mouse, rabbit, rat |
151 |
Propylene glycol dicaprylate/dicaprate |
Rat |
152 |
Propylparaben |
Minipig |
153 |
PVP VA 64 |
Dog, rat |
154 |
RAMEB |
Nonhuman primate |
155 |
Safflower oil |
Dog |
156 |
Salicylic acid |
Minipig |
157 |
Saline(pH adjusted, pH 4.5) |
Dog, mouse, rabbit, rat |
158 |
Sesame oil |
Minipig |
159 |
Shea butter |
Rat |
160 |
Simethicone |
Dog, mouse, nonhuman primate, rat |
161 |
Sodium acetate trihydrate buffer |
Mouse, nonhuman primate |
162 |
Sodium chloride |
Cat, dog minipig, mouse, nonhuman primate, rabbit, rat |
163 |
Sodium citrate |
Nonhuman primate, rat |
164 |
Sodium dihydrogen phosphate dihydrate |
Mouse, nonhuman primate |
165 |
Sodium hydroxide |
Minipig, mouse, nonhuman primate, rat |
166 |
Sodium lauryl sulfate |
Dog, rat |
167 |
Sodium metabisulfite |
Mouse, nonhuman primate, rat |
168 |
Sodium methylparaben |
Minipig, mouse, rat |
169 |
Sodium phosphate buffer |
Dog, mouse, nonhuman primate, rat |
170 |
Sodium propylparaben |
Mouse, rat |
171 |
Sodium succinate |
Dog, mouse rat |
172 |
Sodium sulfite |
Rabbit |
173 |
Solutol HS15TM(see also Kolliphor HS15TM) |
Dog, mouse, nonhuman primate, rat |
174 |
Sorbitan tristearate |
Minipig |
175 |
Sorbitol |
Dog, nonhuman primate, rat |
176 |
Soybean oil |
Dog, minipig, rat |
177 |
Squalane NF |
Minipig |
178 |
Stearic aicd |
Minipig |
179 |
Steayl alcohol |
Minipig |
180 |
Sucrose |
Cat, dog, nonhuman primate, rabbit, rat |
181 |
Sucrose acetate isobutyrate |
Cat |
182 |
Sulfobutyl ether β-cyclodextrin |
Mouse |
183 |
Tartaric acid |
Rabbit, rat |
184 |
Terbinafine HCLTM placebo nail lacquer |
Pig |
185 |
Tetraglycol |
Minipig, rat |
186 |
TranscutolTM |
Cat, dog, guinea pig, minipig, mouse, rabbit, rat |
187 |
Trehalose |
Dog, rat |
188 |
Tris buffer |
Minipig, nonhuman primate |
189 |
Trisodium citrate dihydrate |
Dog, hamster, mouse, rat |
190 |
Tween 20TM |
Dog, minipig, mouse, nonhuman primate, rat |
191 |
Tween 80TM |
Dog, guinea pig, hamster,minipig, mouse, nonhuman primate, rabbit, rat |
192 |
Vitamin E |
Dog, rabbit, rat |
193 |
Vitamin E TPGS |
Dog, mouse, rabbit, rat |
194 |
Water(Note: only combination formulations expressly listing water in their ingredients are listed here) |
Dog, guinea pig, minipig, mouse, nonhuman primate, pig, rabbit, rat |
195 |
White wax |
Minipig |
196 |
Xylitol |
Nonhuman primate |