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주요 부형제 독성정보 : 자세한 자료가 필요하면 CND로 연락주세요 (asancnd.com)
 
번호 물질 독성자료가 있는 동물종
1 Acacia Nonhuman primate, rat
2 Acetate buffer Nonhuman primate, minipig, mouse, rat
3 Acetic acid Dog, mouse, rat
4 Acetone Guinea pig, mouse, rabbit, rat
5 Acetonitrile Dog
6 Acetylated lanolin alcochol Minipig
7 Acetylmethylamide Nonhuman primate
8 Alcohol denatured SDA Minipig
9 Alginic acid Rat
10 Anecortave acetate Rat
11 Antifoam 1510-USTM Rat
12 Avicel CL-611TM Dog
13 Balanced salt saline Rabbit
14 Basal salt solution Mouse
15 Benzonic acid Rat
16 Benzyl alcohol Cat, Dog, nonhuman primate, rat
17 β-Cyclodextrin Dog, mouse, nonhuman primate, rat
18 BHA Minipig
19 BHT Cat, Dog, nonhuman primate, rat
20 Bicarbonate buffer Mouse
21 Calcium chloride Mouse
22 Canola oil Dog
23 Capmul MCMTM Nonhuman primate
24 Capmul MCM NFTM Dog, rat
25 Capmul PG 8TM Dog, rat
26 Capryol 90TM Dog, rabbit, rat
27 CaptisolTM Dog, mouse, nonhuman primate, rat
28 Carbomer 974PTM Minipig, mouse
29 Carbopol Ultrez 10TM Minipig
30 Carboxymethylcellulose Dog, minipig, mouse, nonhuman primate, rabbit, rat
31 Carboxymethylcellulose calcium Dog
32 Carboxymethylcellulose sodium Mouse, rabbit, rat
33 CavisolTM Dog, rat
34 Cetostearyl alcohol Minipig
35 Cetyl acetate Minipig
36 Cetyl alcohol Minipig, mouse
37 Citrate buffer Dog, nonhuman primate, rat
38 Citric acid buffer Cat, dog, nonhuman primate, rat
39 Coconut oil Minipig
40 Collagen matrix Nonhuman primate, rabbit
41 Corn oil Chicken embryo, dog, mouse, nonhuman primate, rabbit rat
42 Cottonseed oil Dog
43 Cyclodextrin Rat
44 Cyclohexane Rabbit, rat
45 Cyclomethicone NF Minipig
46 DAM Dog, rat
47 Dextrose Cat, dog, minipig, nonhuman primate, rabbit, rat
48 Dichlorvos Nonhuman primate
49 Diethylacetamide Cat, chicken, dog, mouse, rabbit, rat
50 Diethylene glycolmonoethyl ether Nonhuman primate
51 Dimethicone Rabbit
52 Dimethiconol blend 20 Minipig
53 Dimethylacetamide Chicken, dog, mouse, rabbit, rat
54 Dimethyl sulfoxide Dog, guinea pig, minipig, mouse, nonhuman primate, rabbit, rat
55 Disodium hydrogen phosphate dihydrate Nonhuman primate
56 Docosanol Minipig
57 Dulbecco's modified PBS Rat
58 Dulbecco's PBS Rat
59 EDTA Minipig, nonhuman primate, rat
60 Ethanol Dog, guinea pig, minipig, mouse, nonhuman primate, rat
61 Fumaric acid Dog
62 Gelatin Dog, nonhuman primate,
63 Gelatin phosphate buffer Minipig
64 GelucireTM Minipig
65 Gelucire 44/14TM Dog, minipig, mouse, rabbit, rat
66 Gelucire 50/13TM Rat
67 Gluconic acid Dog, rat
68 Glycerol Dog, guinea pig, minipig, mouse, nonhuman primate, rabbit, rat
69 Glyceryl stearate SE Minipig
70 Glycofurol Dog
71 Glycol dimethacrylate crosspolymer Rat
72 Gum tragacanth Mouse
73 Gum xanthan Minipig, rabbit, rat
74 Hexylene glycol Minipig
75 Histidine Dog, rat
76 Hydrochloric acid Dog, rat
77 Hydrogenated castor oil Minipig
78 Hydroxyethylcellulose Rat
79 Hydroxypropyl β-cyclodextrin Dog, mouse, nonhuman primate, rat
80 Hydroxypropyl cellulouse Minipig, rat
81 Hydroxypropyl methylcellulose Dog, minipig, mouse, nonhuman primate, rat
82 Hydroxypropyl methylcellulose acetate succinate Dog, minipig, mouse, rabbit, rat
83 Hymetellose Rabbit
84 Hypotonic PBS Dog, rat
85 Imwitor 742TM Hamster, nonhuman primate, rat
86 Isopropyl alcohol Dog, rabbit
87 Isopropyl myristate Minipig, mouse, rabbit
88 Isotonic saline Rat
89 KolliphorTM Nonhuman primate
90 Kolliphor ELTM Dog, mouse, nonhuman primate, rat
91 Kolliphor ELPTM Dog
92 Kolliphor HS15TM (see also Solutol HS15) Minipig
93 Kolliphor RH40TM Dog, rat
94 Labrafil M1944TM Dog, rabbit, rat
95 LabrasolTM Dog, minipig, rabbit, rat
96 Lactated Ringer's Nonhuman primate
97 Lactic acid Dog, rat
98 Lactose Dog, nonhuman primate, rat
99 Lanolin Minipig, rabbit
100 Lanolin alcohol NF Minipig
101 L-Arginine HCl USP Minipig, nonhuman primate
102 L-Ascorbic acid Rat
103 Lauroglycol 90TM Rabbit, rat
104 Maltitol solution Rat
105 Maltol Guinea pig, rabbit
106 Mannitol Dog, minipig, mouse, nonhuman primate, rabbit, rat
107 Methanesulfonic acid Rat
108 MethocelTM Nonhuman primat, rat
109 Methyl methacrylate Rat
110 Methylcellulose Dog, guinea pig, mouse, nonhuman primate, rabbit, rat
111 Methylparaben Minipig
112 Methylpyrrolidone Dog, minipig, mouse
113 Mineral oil Cat, dog, guinea pig, minipig, mouse, rat
114 Myristyl alcohol Minipig
115 Neobell 1053 OilTM Mouse, rat
116 Octoxynol-40 Dog, rabbit
117 Oleic acid NF Minipig
118 Oleyl alcohol NF Minipig
119 Olive oil Minipig, rat
120 Ora-PluseTM suspension Rat
121 Panthenol Minipig
122 Peanut oil Dog, rat
123 Peceol Dog, rat
124 PEG 200 Minipig, nonhumand primate, rabbit, rat
125 PEG 300 Cat, dog, guinea pig, mouse, rabbit, rat
126 PEG 400 Dog, guinea pig, minipig, mouse, nonhuman primate, minipig, rabbit, rat
127 PEG 600 Rat
128 PEG 810 Rat
129 PEG 1000 Mouse, rabbit, rat
130 PEG 1500 Rat
131 PEG 1540 Dog, rabbit, rat
132 PEG 4000 Dog, mouse, rabbit, rat
133 PEG 6000 Rabbit, rat
134 PEG 10000 Rat
135 PEG 400000 Rat
136 Petrolatum Rabbit
137 Phenoxyethanol Minipig, mouse
138 Phosal 53 MCTTM Rat
139 Phosphate Nonhuman primate
140 Phosphate buffer Rat
141 Phosphate-buffered saline Dog, minipig, mouse, nonhuman primate, rabbit, rat
142 Polawax Minipig, mouse
143 Poloxamer 124TM Dog, mouse, rat
144 Poloxamer 188TM Dog, minipig, mouse, nonhuman primate, rabbit, rat
145 Polyethylene terephthalate Rat
146 Poly(glycolide-co-DL-lactide) microspheres Dog
147 Polyglyceyl oleate Rabbit, rat
148 Polyvinylpyrrlidone Dog, nonhuman primate, rabbit, rat
149 Potassium chloride Minipig
150 Propylene glycol Dog, minipig, puinea pig, nonhuman primate, mouse, rabbit, rat
151 Propylene glycol dicaprylate/dicaprate Rat
152 Propylparaben Minipig
153 PVP VA 64 Dog, rat
154 RAMEB Nonhuman primate
155 Safflower oil Dog
156 Salicylic acid Minipig
157 Saline(pH adjusted, pH 4.5) Dog, mouse, rabbit, rat
158 Sesame oil Minipig
159 Shea butter Rat
160 Simethicone Dog, mouse, nonhuman primate, rat
161 Sodium acetate trihydrate buffer Mouse, nonhuman primate
162 Sodium chloride Cat, dog minipig, mouse, nonhuman primate, rabbit, rat
163 Sodium citrate Nonhuman primate, rat
164 Sodium dihydrogen phosphate dihydrate Mouse, nonhuman primate
165 Sodium hydroxide Minipig, mouse, nonhuman primate, rat
166 Sodium lauryl sulfate Dog, rat
167 Sodium metabisulfite Mouse, nonhuman primate, rat
168 Sodium methylparaben Minipig, mouse, rat
169 Sodium phosphate buffer Dog, mouse, nonhuman primate, rat
170 Sodium propylparaben Mouse, rat
171 Sodium succinate Dog, mouse rat
172 Sodium sulfite Rabbit
173 Solutol HS15TM(see also Kolliphor HS15TM) Dog, mouse, nonhuman primate, rat
174 Sorbitan tristearate Minipig
175 Sorbitol Dog, nonhuman primate, rat
176 Soybean oil Dog, minipig, rat
177 Squalane NF Minipig
178 Stearic aicd Minipig
179 Steayl alcohol Minipig
180 Sucrose Cat, dog, nonhuman primate, rabbit, rat
181 Sucrose acetate isobutyrate Cat
182 Sulfobutyl ether β-cyclodextrin Mouse
183 Tartaric acid Rabbit, rat
184 Terbinafine HCLTM placebo nail lacquer Pig
185 Tetraglycol Minipig, rat
186 TranscutolTM Cat, dog, guinea pig, minipig, mouse, rabbit, rat
187 Trehalose Dog, rat
188 Tris buffer Minipig, nonhuman primate
189 Trisodium citrate dihydrate Dog, hamster, mouse, rat
190 Tween 20TM Dog, minipig, mouse, nonhuman primate, rat
191 Tween 80TM Dog, guinea pig, hamster,minipig, mouse, nonhuman primate, rabbit, rat
192 Vitamin E Dog, rabbit, rat
193 Vitamin E TPGS Dog, mouse, rabbit, rat
194 Water(Note: only combination formulations expressly listing water in their ingredients are listed here) Dog, guinea pig, minipig, mouse, nonhuman primate, pig, rabbit, rat
195 White wax Minipig
196 Xylitol Nonhuman primate


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